Lipid nanoparticles (LNPs) have emerged as a cornerstone of modern drug delivery, offering a robust platform for improving the solubility, stability, and bioavailability of challenging pharmaceutical compounds. At Ascendia Pharmaceutical Solutions, we specialize in leveraging cutting-edge technology and deep scientific expertise to deliver industry-leading solutions in LNP development and manufacturing. One of our core capabilities in this domain is our microfluidics services, powered by the NanoAssembler™—a versatile and efficient tool that supports the seamless transition from development to commercial-scale production.
The NanoAssembler™ Advantage
Ascendia’s microfluidics capabilities are centered on the NanoAssembler platform, a suite of devices designed to create highly reproducible and scalable LNP formulations. Our portfolio includes three models: the Ignite (for small-scale screening), the Blaze™ (for medium-scale production), and the GMP system (for large-scale and commercial manufacturing). This tiered approach enables us to meet client needs at every stage of the drug development pipeline—from early discovery to commercial production.
Key Features of the NanoAssembler™ Platform:
- Small Footprint: The compact design of the NanoAssembler™ devices makes them an excellent fit for laboratory environments with limited space.
- Versatile Operation: By combining aqueous and organic phases under controlled jet mixing conditions, the NanoAssembler™ generates LNPs with precise size and composition.
- Scalability: Our in-house systems allow seamless scale-up from milliliter quantities in early-stage research to large-scale GMP production, ensuring consistency across all phases.
Expertise Beyond the Equipment
Having state-of-the-art equipment is only part of the equation. What truly sets Ascendia apart is the depth of our expertise in LNP technology. Our team’s extensive experience allows us to address complex challenges, from controlling particle size to optimizing formulations for specific drug compounds. We understand that LNP development is not a one-size-fits-all process, and we collaborate closely with our clients to tailor solutions to their unique needs.
Ascendia Pharmaceutical Solutions’ Differentiators:
- End-to-End Services: Ascendia provides comprehensive support across the entire drug development lifecycle, from formulation design and early-stage screening to commercial manufacturing.
- Regulatory Compliance: Our GMP-certified systems and rigorous quality control processes ensure that our LNPs meet the highest industry standards.
- Collaborative Approach: We engage with clients to understand their goals and challenges, enabling us to deliver customized solutions that maximize the therapeutic potential of their drugs.
Why Choose Ascendia?
In an increasingly competitive CDMO landscape, Ascendia’s holistic approach to LNP development stands out. Our ability to seamlessly transition projects from small-scale development to large-scale manufacturing is unmatched. Few CDMOs offer the breadth of capabilities and expertise that Ascendia brings to the table. Clients choose us not only for our advanced technology but also for our proven track record of success in tackling complex pharmaceutical challenges.
What We Offer:
- Specialized Knowledge: Decades of experience in lipid nanotechnology and a deep understanding of the science behind LNPs.
- Integrated Capabilities: On-site microbial testing, endotoxin assessments, and regulatory support streamline the drug development process.
- Commitment to Excellence: Our dedication to precision, quality, and timely delivery ensures that clients receive unparalleled service.
Educating and Empowering Clients
At Ascendia, we prioritize education and transparency. We recognize that many clients come to us at various stages of the drug development pipeline, often seeking guidance on how to navigate the complexities of LNP technology. Through publications, technical marketing, and collaborative discussions, we empower clients with the knowledge they need to make informed decisions.
A One-Stop Solution
As we expand our capabilities with the construction of a new Phase III and commercialization facility, Ascendia is poised to become a one-stop solution for drug developers. From early discovery and formulation development to large-scale production, we offer a seamless pathway to bring life-changing therapies to market.
Ascendia’s combination of cutting-edge technology, unparalleled expertise, and a client-centric approach makes Ascendia Pharmaceutical Solutions the partner of choice for lipid nanoparticle microfluidics services. The NanoAssembler™ platform is more than just a tool—it is a gateway to innovation and success in drug delivery.
To learn more about how we can solve your complex drug development projects, contact us.